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Early Grade Repetition and Inattention Associated With Neurofibromatosis Type 1

Cuques Pediatric Center, Aix-en-Provence, France, fxcoude{at}tiscali.fr

Claire Mignot, MD

Cuques Pediatric Center, Aix-en-Provence, France

Stanislas Lyonnet, MD, PhD

Département de Génétique, Hôpital Necker, Paris, France

Arnold Munnich, MD, PhD

Département de Génétique, Hôpital Necker, Paris, France

Objective: The authors analyze the occurrence of grade repetition and inattention in children diagnosed with neurofibromatosis type 1 (NF1). Method: The participant group consisted of 310 patients with NF1 and a control group of 242 individuals. The number of grade repetitions for each participant during his or her time in elementary, middle, and high school was noted and the inattention score was calculated from the Barkley's ADHD Clinic Parent Interview form. Results: Fifty-three percent of NF1 patients versus 25% of the controls had increased grade repetition, P2 (1) = 27.41, p < .0001, and 67% of NF1 patients versus 14% of controls were found to be inattentive, 2 (1) = 27.41, p < .0001. Repetition mainly affected kindergarten and first-grade levels and the inattention score significantly correlated with grade repetition prevalence in NF1 patients (r2 = .7429, p < .0004). Conclusion: Grade repetition is a frequent complication in NF1 and correlates with inattention in individuals with this disease. (J. of Att. Dis. 2007; 11(2) 101-105)

Key Words: neurofibromatosis type 1 • learning disorders • ADHD

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This version was published on September 1, 2007

Journal of Attention Disorders, Vol. 11, No. 2, 101-105 (2007)
DOI: 10.1177/1087054707299398


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This Article Abstract Free Full Text (Free PDF) Free Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Coudé, F. X. Articles by Munnich, A. Search for Related Content PubMed PubMed Citation Articles by Coudé, F. X. Articles by Munnich, A. Social Bookmarking                         What's this?