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Methylphenidate effects on children with Attention Deficit Hyperactivity Disorder: Self-report of symptoms, side-effects, and self-esteem

Lehight University

A.D. Anastopoulos

University of North Carolina-Greensboro

D. Kwasnik

University of Massachusetts Medical Center

R.A. Barkley

University of Massachusetts Medical Center

M.B. McMurray

University of Massachusetts Medical Center

George J. DuPaul, PhD

School Psychology Program, Lehigh University, 11 Research Drive, Bethlehem, PA 18015

Examined the effects of methylphenidate (MPH) on the self-report ratings of 24 children with Attention Deficit Hyperactivity Disorder (ADHD). Children provided ratings of ADHD symptoms, side-effects, and self-esteem in a double-blind, placebo-controlled evaluation of three MPH doses (.16 mg/kg, .29 mg/kg, .42 mg/kg). Mothers and teachers completed ratings of ADHD symptoms and side-effects. Children reported significant improvements in ADHD symptoms with medication in an analogous fashion to parent and teacher ratings. Regardless of dose, children reported some side-effects to be more severe than did parents or teachers. Children reported marginally significant increases in side-effect severity with MPH vs. placebo whereas teachers reported significant reductions in the severity of side-effects with treatment. The low dose led to significant improvements in children's behavioral self-concept compared to placebo, although most children showed no overall change in self-concept. These results highlight the importance of children's perceptions of MPH treatment for research and clinical purposes.

Journal of Attention Disorders, Vol. 1, No. 1, 3-15 (1996)
DOI: 10.1177/108705479600100101


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